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Cajun Roast Beef Po’ Boys Classic Southern Sandwich with a Kick

  • Author: Chef Mia
  • Prep Time: 20 minutes
  • Cook Time: 3 hours
  • Total Time: 3 hours 20 minutes
  • Yield: 4 1x
  • Method: Main Course
  • Cuisine: Southern

Description

A classic Southern po’ boy sandwich filled with tender Cajun-spiced roast beef, topped with crunchy lettuce, tomatoes, and a spicy mayo, served on crispy French bread.


Ingredients

Scale
  • For the Roast Beef:
  • 2 lbs beef chuck roast
  • 2 tablespoons Cajun seasoning
  • 1 tablespoon olive oil
  • 1 teaspoon salt
  • 1/2 teaspoon black pepper
  • 1/2 teaspoon garlic powder
  • 1/2 teaspoon onion powder
  • For the Spicy Mayo:
  • 1/2 cup mayonnaise
  • 1 tablespoon hot sauce (such as Tabasco)
  • 1 teaspoon Cajun seasoning
  • 1 teaspoon lemon juice
  • For the Sandwich:
  • 4 (6-inch) French bread rolls, split and toasted
  • 2 cups shredded iceberg lettuce
  • 1 large tomato, sliced
  • 1/2 red onion, thinly sliced
  • Pickled okra or dill pickle slices (optional)

Instructions

  1. 1. Season the beef: In a small bowl, mix Cajun seasoning, salt, pepper, garlic powder, and onion powder. Rub the mixture all over the beef chuck roast.
  2. 2. Sear the beef: Heat olive oil in a large Dutch oven or heavy-bottomed pot over medium-high heat. Sear the roast on all sides until browned, about 3-4 minutes per side.
  3. 3. Slow cook: Add 1 cup of water or beef broth to the pot. Cover and cook on low heat (or in a 300°F oven) for 2.5 to 3 hours, until the beef is fork-tender.
  4. 4. Shred the beef: Remove the roast from the pot and shred it using two forks. Discard any excess fat. Return the shredded beef to the pot with the cooking juices and keep warm.
  5. 5. Make the spicy mayo: In a small bowl, combine mayonnaise, hot sauce, Cajun seasoning, and lemon juice. Stir well and set aside.
  6. 6. Assemble the po' boys: Spread spicy mayo on the cut sides of each French roll. Layer with shredded roast beef, lettuce, tomato slices, and red onion. Add pickled okra or pickles if desired.
  7. 7. Serve immediately, or lightly toast the assembled sandwiches under the broiler for 1-2 minutes for a warm, crispy finish.

Notes

For an even spicier kick, add sliced jalapeños or increase the hot sauce in the mayo. Leftover shredded beef can be stored in the refrigerator for up to 3 days.


Nutrition

  • Calories: 650
  • Sugar: 6g
  • Fat: 32g
  • Carbohydrates: 45g
  • Protein: 42g